Martinsburg is located in northeastern West Virginia, in the Eastern Panhandle. Situated in a region of dairy farms and fruit orchards, it is a commercial, manufacturing, and transportation center. Manufactures include glass and wood products, construction materials, clothing, processed food, and explosives. Major private employers in and around Martinsburg include Quad/Graphics, EcoLab, Orgill, Quebecor World, Sino-Swearingen, and FedEx. The city is also the location of several regional governmental facilities, such as the Internal Revenue Service Computing Center. A 2006 real estate survey has estimated the population of Martinsburg, West Virginia at 16,392.